Q: How do I order a test?

To order your test, simply choose the test you wish from the Shop menu, found at the top of the web page, use the contact form or email us at “info@genorama.com”. You can read more about different tests when clicking on them from the catalogue.

Q: How do I register my test and access the results?

To ensure the utmost security and confidentiality, we have developed a dedicated client portal exclusively for our clients’ test results. To initiate the process, kindly register your test through the portal linked here. You’ll find a unique code inside the test package, which you’ll need for registration.

Upon registering, we kindly request that you complete a brief survey. This allows us to gather essential information for a comprehensive analysis of your sample. Once the survey is submitted, your test will be officially registered. You can then proceed to send your sample back to us following the instructions enclosed in the package.

We advise you to retain the package box for returning the sample. Upon receipt of your sample, our team will promptly commence the analysis. Once completed, the results will be securely uploaded to the client portal. You can access and download your results using a 2-factor authentication process that was established during the registration phase.

Please be aware that for privacy and security reasons, we are obliged to remove the results from the client portal after a certain period passes since you downloaded your results. We recommend that you retain a copy of your results for future reference. If you have any concerns or require further assistance, please do not hesitate to contact our support team.

We prioritize the security of your data and results. With our two-factor authentication and encrypted online user portal, we ensure that only you can access your genetic test results. Regular security audits and compliance with data protection regulations further strengthen our commitment to protecting your information.

Collecting a buccal cell sample

Biological relationship testing makes it possible not only to establish paternity but also to identify other biological links, including siblingship or grandparents. Biological relationship tests are based on a mathematical comparison of the allele values of the individuals tested and the allele frequencies in the population.

In paternity testing, the parties involved are the alleged father and the child(ren). Generally, a child inherits two alleles from its parents in each DNA locus, one from the mother and the other from the father, so to confirm paternity or maternity, the child and parent must share one allele in each locus tested. Including the mother’s sample in paternity testing can make a significant difference to the likelihood of paternity, as it is possible to identify the DNA alleles that are inherited from the father. Without the inclusion of a maternal sample, research has shown a higher incidence of false positive paternity estimates. In this case, the alleles shared by the child and the tested male may not in fact be inherited from the particular tested male, but may in fact be inherited from the mother, so that the allele biologically inherited from the father may not be present in the particular male, and the tested male may not be biologically the father of the child.

Paternity testing compares the alleles of the presumed father and child in specific DNA regions. The result of the test is to rule out or confirm paternity. A positive result indicates that there is at least a 99.99% probability that the child is the biological father. A negative result indicates with 100% probability that biological paternity has been excluded. The test results are not usable in court proceedings due to the unverifiability of the sampling, unless all the persons are tested at the same time on the spot and their identities are identified by means of an identity document.

Scientific studies have shown that changes (mutations) can occur in gamete DNA which are passed on to offspring. In the case of genetic testing, this means that the alleles that are identified can be lengthened or shortened, i.e. the numerical value that we show in the report changes from one locus to the next. The mutation frequencies vary between regions of the DNA and are less than 1% for the loci used in the detection (for example, the mutation frequency of the TH01 loci in the male line is 0.009%, the mutation frequency of the D3S1358 loci is 0.13%, the mutation frequency of the D18S51 loci is 0.22% and the mutation frequency of the FGA loci is 0.32%). This means that during the formation of spermatozoa, random changes in the DNA can occur that result in the father and the child not sharing an allele at a particular DNA locus.

Due to automatic email filters, not all emails might get delivered. Adding our domain address to your approved sender list (Whitelisting) ensures that the emails we send do not go to spam. Whitelisting is not complicated and only takes a few minutes if you follow the instructions. You will find instructions for different email service providers below. In order to add us to the list, you can follow the instructions or contact your network administrator and/or IT support and ask to have emails from our domain (@genorama.com) whitelisted.

Whitelisting emails

• In Outlook Go to the Home tab. Click on Junk –> Junk Email Options In the Junk Email Options section, navigate to the Safe Senders tab, and click Add. In the Add address or domain box, enter @genorama.com (or genorama.com) and click OK in order to save the change.
• In Outlook mobile app Open Outlook Mobile App. Click on the message that you want to whitelist. Click on the three dots in the top right corner. Click “Move to focused inbox”. When the pop-up screen comes up, click “Move this and all future messages”.
• In Gmail The Gmail whitelist process can be done quickly through the web client: Click the settings button (in the top-right corner of the screen), then select “Settings” from the resulting drop-down menu. Navigate to the tab labelled “Filtered and Blocked Addreses” Select “Create a new filter” and enter the emails or domains you want to whitelist. To whitelist every sender from Genorama LLC, type the domain alone, such as “@genorama.com”. This will tell Gmail to approve every message from a us. Click “Create filter” to approve the new filter, then mark “Never send to Spam” to whitelist every email within the filter. You can also choose to Star these emails, apply a given label, or mark them as important.
• In Gmail mobile app Open the Gmail application. Navigate to Spam or Junk Folder. Click on the message you wish to view. Select the option “Report not spam”. You will now receive messages from this sender as normal.
• In Hotmail Login to your Hotmail, click on the Settings icon at the top right side of the page, expand it and click on More Mail Settings Click on Safe and blocked senders Click Safe Senders Insert the email address you want to whitelist, then click Add to list. To whitelist every sender from Genorama LLC, type the domain alone, such as “@genorama.com”. Email address has been whitelisted and will skip spam check by Hotmail.

Diagnostic testing is used to precisely identify the disease that is making a person ill. The results of a diagnostic test may help you make choices about how to treat or manage your health.

Predictive and pre-symptomatic genetic tests are used to find gene changes that increase a person’s likelihood of developing diseases. The results of these tests provide you with information about your risk of developing a specific disease. Such information may be useful in decisions about your lifestyle and healthcare.

Carrier testing is used to find people who “carry” a change in a gene that is linked to disease. Carriers may show no signs of the disease; however, they have the ability to pass on the gene change to their children, who may develop the disease or become carriers themselves. Some diseases require a gene change to be inherited from both parents for the disease to occur. This type of testing usually is offered to people who have a family history of a specific inherited disease or who belong to certain ethnic groups that have a higher risk of specific inherited diseases.

Prenatal testing is offered during pregnancy to help identify fetuses that have certain diseases.

Newborn screening is used to test babies one or two days after birth to find out if they have certain diseases known to cause problems with health and development.

Pharmacogenomic testing gives information about how certain medicines are processed by an individual’s body. This type of testing can help your healthcare provider choose the medicines that work best with your genetic makeup.

Research genetic testing is used to learn more about the contributions of genes to health and to disease. Sometimes the results may not be directly helpful to participants, but they may benefit others by helping researchers expand their understanding of the human body, health, and disease.

Hopefully You will find the explanation to the term You are looking for down below.

Allele:

Allele: one of the possible forms of a gene.

Autosomal:

Autosomal: a trait or condition caused by a gene on an “autosome”, meaning chromosomes 1 through 22. In other words, a characteristic not connected with the X or Y chromosome. Examples of autosomal genetic conditions include: Cystic Fibrosis and Sickle Cell Anemia.

Benign Variant:

Benign variant: a DNA change that does not affect a gene’s function or cause a health problem. We all have many benign variants that make us unique from each other that do not cause medical issues.

Buccal Sample:

Buccal sample: a way to collect DNA from the cells on the inside of a person’s cheek, either through a saliva sample or cheek swab.

Carrier Testing/Screening:

Carrier testing/screening: a medical test that is typically performed for family planning which helps intended parents know if they carriers for certain inherited genetic conditions, and if they have carrier conditions in common, whether their children could be at-risk.

CGC (Certified Genetic Counselor):

CGC (Certified Genetic Counselor): a credential held by genetic counselors in the United States that is received after passing an examination that demonstrates their skills and knowledge as a healthcare professional.

Chorionic Villus Sampling:

Chorionic villus sampling (CVS): a test done by taking cells from the placenta in early pregnancy to detect genetic conditions in the fetus.

Chromosome:

Chromosome: DNA is packaged into structures called chromosomes, found in the cells of living things. Humans have 46 chromosomes that come in 23 pairs. The first are numbered 1-22, and are called “autosomes”. The last chromosomes pair are called sex chromosomes: females usually have XX chromosomes, and males usually have XY.

DNA:

DNA: the building block of life contained in each of our cells that carries our genetic information.

Diagnostic Testing:

Diagnostic testing: a medical test that provides information that allows a physician to diagnose a condition.

DNA Testing:

DNA testing: a form of genetic test that specifically analyzes DNA. This type of testing may be used to identify DNA changes that can cause disease, or it may be done to learn other genetic information about an individual, such as paternity or ancestry.

Direct-to-Consumer Testing:

Direct-to-consumer testing: also known as at-home DNA testing or DTC testing, these are tests that are marketed directly to consumers and enables them to purchase various types of genetic tests and receive the results without the involvement of a personal physician or insurance company.

Exome:

Exome: the portion of DNA which contains the genes, which is approximately 1-2% of all our DNA.

Gene:

Gene: a segment of DNA which contains a specific instruction for the body. This tells the body how to make a protein, which is a building block of the body. Genes are inherited and also determine characteristics of an individual, such as eye color or whether or not they have certain genetic diseases.

Genetic Counselor:

Genetic Counselor: a healthcare professional who has training in genetics and counseling who works alongside doctors, nurses, or other members of your healthcare team. Genetic counselors assess your medical history and family history to determine if you are at risk for a genetic or hereditary condition and discuss the implications of available genetic testing options.

Genetic Risk:

Genetic risk: the contribution our genes play in the chance that we will develop a certain illness or condition.

Genetic Testing:

Genetic testing: analyzing a person’s genetic material (i.e. chromosomes or genes) in order to identify changes which could lead to genetic disease or predisposition to disease.

Genotype:

Genotype: describes your genetic makeup. This term is usually used when referring to a particular trait.

Germline Testing:

Germline testing: typically performed on a blood or saliva sample to look for inherited genetic changes or changes that someone has from birth, which can be passed down from one generation to the next.

Genetic Information Nondiscrimination Act (GINA):

Genetic Information Nondiscrimination Act (GINA): a federal law passed in 2008 that protects people from their genetic information being misused and impacting their health insurance coverage or employment.

Informed Consent:

Informed consent: the process of learning key details about a medical treatment (such as a drug, surgery or test) to be able to decide whether or not to have the treatment or test.

Likely Pathogenic Variant:

Likely pathogenic variant: a DNA change we think likely causes a gene not to work and may lead to a health problem. Usually, scientists and doctors are 90% sure these cause disease, but not enough evidence has been collected to be 100% sure yet.

Mutation (Genetic Mutation):

Mutation (genetic mutation): a change in DNA from its original state. Some mutations do not cause any problems, while others result in disease; however, this term is most often used when an individual has a genetic change that causes a health condition.

Pathogenic Variant:

Pathogenic variant: a change in the DNA that is known to cause a gene not to work and may lead to a health problem.

Personalized Medicine:

Personalized medicine: term used to describe an emerging healthcare approach that tailors disease prevention and/or treatment based on an individual’s genes, environment, lifestyle, and other factors.

Preimplantation Genetic Testing (PGT):

Preimplantation genetic testing (PGT): screening test performed during in vitro fertilization (IVF). There are three types: PGT-M, PGT-SR, and PGT-A, each involving testing of an embryo for certain genetic conditions (such as cystic fibrosis or Down syndrome). This type of testing was formerly called preimplantation genetic diagnosis (PGD).

Recessive:

Recessive: a form of a gene that is masked by the alternate (dominant) form of the gene and is only expressed when the person has two of these non-dominant (recessive) copies. This is also referred to as the recessive allele.

Sequencing:

Sequencing: a test that reads through the DNA code letter by letter to look for changes that can cause health problems. This test can be done on a single gene, a panel of genes, or on even more of the DNA (genome or exome).

X-Linked:

X-linked: trait or condition caused by a gene on the X-chromosome.

SNP (Single Nucleotide Polymorphism) Testing:

SNP (single nucleotide polymorphism) testing: testing that looks for single letter changes within the DNA. (This is different than sequencing an entire gene or genome)

Tumor/Somatic Testing:

Tumor/somatic testing: testing that is done on cells from a tumor or cancer to look for DNA changes. Knowing the DNA profile of a tumor can help doctors tailor treatment. Most DNA changes found in a tumor are not inherited and not present in a person’s healthy cells.

Variant:

Variant: a change in your DNA instructions (like a change in the spelling of a word) that is different than what most people have. It may or may not change the way the gene works.

VUS (Variant of Uncertain/Unknown Significance):

VUS (Variant of Uncertain/Unknown Significance): a change in the DNA instructions that scientists and doctors are unsure yet if it causes a health problem.